ombitasvir/paritaprevir/ritonavir & dasabuvir (DSC) will improve the stage or outcome of ergotamine by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Contraindicated. Acute ergot toxicity characterized by vasospasm and tissue ischemia is connected to coadministration of ritonavirErgotamine: Alpha-adrenergic blocking agent with direct stimul